Project Description: Currently, there are few facilities to detect and characterize emerging pathogens, including SARSCoV-2 in Tanzania (a total of 4 next generation sequencing (NGS) machines are available for the entire country: see recent publication in The Lancet, enclosed). Antimicrobial resistance (AMR) is a highly relevant problem in the management of HIV, TB and malaria patients globally, but currently existing capacity and infrastructure in Tanzania do not allow large-scale detection of AMR for these diseases. Detecting transmission... Currently, there are few facilities to detect and characterize emerging pathogens, including SARSCoV-2 in Tanzania (a total of 4 next generation sequencing (NGS) machines are available for the entire country: see recent publication in The Lancet, enclosed). Antimicrobial resistance (AMR) is a highly relevant problem in the management of HIV, TB and malaria patients globally, but currently existing capacity and infrastructure in Tanzania do not allow large-scale detection of AMR for these diseases. Detecting transmission hot-spots is crucial for the control and surveillance of infectious diseases, such as COVID-19, TB and HIV, as well as improving diagnostic capacity for non-malarial causes of febrile illnesses and zoonotic diseases is much needed, but gene sequencing facilities in Tanzania are scarce. Further, there is a significant lack of teaching and training facilities in Tanzania for young medical staff and researchers in the use of molecular tools for routine medical work and clinical research.
Principal Investigator : Brian Tarimo
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Time frame: (2022-07-01) - (2024-06-30)